The name Zhyrko is formed by truncation and suffixation from the Old Slavic personal name Zhyroslav or Moizhir using the suffix -ko, where the element -zhyr- is employed in its ancient meaning of 'life', 'food', 'pasture'. The name Zhyrko is documented in the Registers of Zaporizhian Cossacks from 1649. For example, Andrus Zhyrko is mentioned in the records. In Poland, the anthroponym Zhyrko is already recorded in sources from the 14th to 15th centuries. Comparatively, the records show the forms Żirko and Sirko.