Tsanko is a South Slavic diminutive name derived from the names Tsan'o or Tsano, which evolved as a phonetic variation of full personal names like Stanyo, Stano, Stanimir, Stamen, and Stoyan. This name formed based on another name starting with the initial sound cluster /S T/ (Ilchev 225-226; Grk 206; Śim 402). The earliest records of this name date back to the period when surnames began to emerge as a distinct class of anthroponyms. For example:
- 1450: Chanko — Verbovets village, Veryatsia (Szabó 527, 545); - 1570: Lad. Caniko — Lokhovo village (Chu Prizv. 589); - 1682: Cianko Ivan — Bistrа village (LehBer 163).