The name 'Puzylo' is likely a derivative with a nuance of coarseness, formed from the nickname type 'Puzi' with the suffix '-ilo'. A document from 1463 states: "Prince Hlib Ivanovych, Prince Yuriy, the servant from Holovch Pozylo" (SSUM II 275). The patronymic 'Puzovsky' is also mentioned there, referring to the city of Brest. Additionally, in Belarusian documents from 1541, the personal name 'Puz Mykievich' is mentioned (Bir 249).